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Ligand efficiency beyond the rule of 5

Molecular Design · published 10 March 2016

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http://en.wikipedia.org/wiki/Ligand_efficiency

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http://dx.doi.org/10.1021/acsmedchemlett.5b00157

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http://en.wikipedia.org/wiki/Lipinski%27s_rule_of_five

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http://dx.doi.org/10.1016/S0169-409X(96

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Dans la merde Read at the source ↗

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http://dx.doi.org/10.1039/C1MD00093D

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http://dx.doi.org/10.1021/ci300010y

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http://dx.doi.org/10.1016/j.chembiol.2014.08.013

dx.doi.org

http://dx.doi.org/10.1021/acs.jmedchem.5b01286

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http://leachresearchgroup.wordpress.com/2015/11/28/synthetic-chemistry-is-for-roundheads-medicinal-chemistry-should-be-for-cavaliers/

leachresearchgroup.wordpress.com

http://blogs.sciencemag.org/pipeline/archives/2015/11/10/one-step-beyond-maybe-more

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http://dx.doi.org/10.1038/nrd4163

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http://dx.doi.org/10.1038/nrd2199

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The boys who cried wolf Read at the source ↗

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http://dx.doi.org/10.1007/s10822-012-9631-5

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http://dx.doi.org/10.1007/s10822-014-9757-8

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Ligand efficiency metrics: why all the fuss? Read at the source ↗

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The homeopathic limit of ligand efficiency Read at the source ↗

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http://dx.doi.org/10.1021/jm201388p

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http://www.youtube.com/watch?v=wIWaJ0sy03g

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http://www.slideshare.net/pwkenny/pwk-fraglib-iqpcoct2008

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