corpus.blog
41554 blogs · [ { "id": "01a0876d-4445-7176-b828-90275d7c3f2e", "title": "Much Ado About Personalized Medicine… or Why the Nose of Biomedical Research Keeps Growing Longer", "url": "https://dirnagl.com/2025/06/18/much-ado-about-personalized-medicine-or-why-the-nose-of-biomedical-research-keeps-growing-longer/", "published_at": "2025-06-18T15:03:37+00:00" }, { "id": "01a0876d-4445-7176-b828-90275d8474d5", "title": "„Research Trek – Aufbruch in ein unbekanntes Wissenschaftssystem“", "url": "https://dirnagl.com/2025/06/17/research-trek-aufbruch-in-ein-unbekanntes-wissenschaftssystem/", "published_at": "2025-06-17T14:39:28+00:00" }, { "id": "01a0876d-4445-7176-b828-90275e41e6d8", "title": "AI in Medicine: Hubris, Hype, and Half-Science", "url": "https://dirnagl.com/2025/04/12/ai-in-medicine-hubris-hype-and-half-science/", "published_at": "2025-04-12T14:57:52+00:00" }, { "id": "01a0876d-4445-7176-b828-90275ea13aaf", "title": "Artificial intelligence: Critique of chatty reasoning", "url": "https://dirnagl.com/2023/06/06/artificial-intelligence-critique-of-chatty-reasoning/", "published_at": "2023-06-06T10:34:01+00:00" }, { "id": "01a0876d-4445-7176-b828-90275f323c1f", "title": "Fraud in science is rare. But is this actually true?", "url": "https://dirnagl.com/2023/03/12/fraud-in-science-is-rare-but-is-this-actually-true-2/", "published_at": "2023-03-12T12:27:28+00:00" }, { "id": "01a0876d-4445-7176-b828-9027601488c6", "title": "Boost your score: Digital narcissism in the competition of scientists", "url": "https://dirnagl.com/2021/05/03/boost-your-score-digital-narcissism-in-the-competition-of-scientists/", "published_at": "2021-05-03T19:00:42+00:00" }, { "id": "01a0876d-4445-7176-b828-902760d581a7", "title": "In the fight against Corona, learning from Botswana means learning to win!", "url": "https://dirnagl.com/2021/03/18/in-the-fight-against-corona-learning-from-botswana-means-learning-to-win/", "published_at": "2021-03-18T12:24:32+00:00" }, { "id": "01a0876d-4445-7176-b828-9027617d6d44", "title": "Judging science by proxies Part II: Back to the future", "url": "https://dirnagl.com/2021/03/13/judging-science-by-proxies-part-ii-back-to-the-future/", "published_at": "2021-03-13T12:50:00+00:00" }, { "id": "01a0876d-4445-7176-b828-902762613959", "title": "Jugdging science by proxies: A short and incomplete history", "url": "https://dirnagl.com/2021/01/03/jugdging-science-by-proxies-a-short-and-incomplete-history/", "published_at": "2021-01-03T10:27:29+00:00" }, { "id": "01a0876d-4445-7176-b828-902762b8c0ae", "title": "Peer review is dead, long live peer review!", "url": "https://dirnagl.com/2020/11/28/peer-review-is-dead-long-live-peer-review/", "published_at": "2020-11-28T16:23:26+00:00" }, { "id": "01a0c508-3b29-72df-b486-26c206a59a1d", "title": "Science meets politics, or: Survival of the ideas that fit", "url": "https://dirnagl.com/2020/11/14/science-meets-politics-or-survival-of-the-ideas-that-fit/", "published_at": "2020-11-14T15:18:24+00:00" }, { "id": "01a0c508-3b29-72df-b486-26c207a5796c", "title": "From mouse to man through the valley of death?", "url": "https://dirnagl.com/2020/09/02/from-mouse-to-man-through-the-valley-of-death/", "published_at": "2020-09-02T16:09:56+00:00" }, { "id": "01a0c508-3b29-72df-b486-26c207e199b5", "title": "Podcast mania", "url": "https://dirnagl.com/2020/08/10/1689/", "published_at": "2020-08-10T10:36:28+00:00" }, { "id": "01a0c508-3b29-72df-b486-26c207fb1c0e", "title": "“The Ioannidis Affair”", "url": "https://dirnagl.com/2020/06/01/the-ioannidis-affair/", "published_at": "2020-06-01T13:47:34+00:00" }, { "id": "01a0c508-3b29-72df-b486-26c208059101", "title": "We don’t need animal experiments! We get our drugs from the pharmacy!", "url": "https://dirnagl.com/2020/04/01/we-dont-need-animal-experiments-we-get-our-drugs-from-the-pharmacy/", "published_at": "2020-04-01T14:04:56+00:00" }, { "id": "01a0c508-3b29-72df-b486-26c20865991d", "title": "World sensation: Increase in life expectancy by more than 10 years!", "url": "https://dirnagl.com/2020/02/13/world-sensation-increase-in-life-expectancy-by-more-than-10-years/", "published_at": "2020-02-13T21:44:19+00:00" }, { "id": "01a0c508-3b29-72df-b486-26c2090dbd89", "title": "Diet: Is nutrition science a more reliable source of advice than your grandmother?", "url": "https://dirnagl.com/2019/12/15/diet-is-nutrition-science-a-more-reliable-source-of-advice-than-your-grandmother/", "published_at": "2019-12-15T16:13:10+00:00" }, { "id": "01a0c508-3b29-72df-b486-26c209fd470a", "title": "Why do WE trust the Intergovernmental Panel on Climate Change, but not the climate skeptics?", "url": "https://dirnagl.com/2019/11/17/why-do-we-trust-the-intergovernmental-panel-on-climate-change-but-not-the-climate-skeptics/", "published_at": "2019-11-17T15:39:11+00:00" }, { "id": "01a0c508-3b29-72df-b486-26c20a00c283", "title": "What you always wanted to know about the p-value, but were afraid to ask", "url": "https://dirnagl.com/2019/10/22/what-you-always-wanted-to-know-about-the-p-value-but-were-afraid-to-ask/", "published_at": "2019-10-22T14:46:58+00:00" }, { "id": "01a0c508-3b29-72df-b486-26c20a84ca29", "title": "When carmakers hack brains", "url": "https://dirnagl.com/2019/09/13/when-carmakers-hack-brains/", "published_at": "2019-09-13T12:34:01+00:00" }, { "id": "01a0c518-bd69-7117-9da3-7ade78ad5dcd", "title": "Love thy NULL result as thy statistically most significant!", "url": "https://dirnagl.com/2019/05/12/love-thy-null-result-as-thy-statistically-most-significant/", "published_at": "2019-05-12T14:36:03+00:00" }, { "id": "01a0c518-bd69-7117-9da3-7ade78ec3cf6", "title": "Nature: Pig brains kept alive outside body for hours after death! Really?", "url": "https://dirnagl.com/2019/04/17/nature-pig-brains-kept-alive-outside-body-for-hours-after-death-really/", "published_at": "2019-04-17T21:34:43+00:00" }, { "id": "01a0c518-bd69-7117-9da3-7ade79abedfe", "title": "Enter the funding lottery!", "url": "https://dirnagl.com/2019/04/13/enter-the-funding-lottery/", "published_at": "2019-04-13T20:33:43+00:00" }, { "id": "01a0c518-bd69-7117-9da3-7ade7a48a288", "title": "On triangulation in experimentation", "url": "https://dirnagl.com/2019/03/16/on-triangulation-in-experimentation/", "published_at": "2019-03-16T18:43:12+00:00" }, { "id": "01a0c518-bd69-7117-9da3-7ade7a8ae318", "title": "Man errs as long as he strives….", "url": "https://dirnagl.com/2019/02/17/man-errs-as-long-as-he-strives/", "published_at": "2019-02-17T16:41:21+00:00" }, { "id": "01a0c518-bd69-7117-9da3-7ade7b1ae0de", "title": "Microbe Mania with Melancholic Microbes", "url": "https://dirnagl.com/2018/12/16/microbe-mania-with-melancholic-microbes/", "published_at": "2018-12-16T16:37:23+00:00" }, { "id": "01a0c518-bd69-7117-9da3-7ade7b3444eb", "title": "Could gambling save science?", "url": "https://dirnagl.com/2018/11/18/could-gambling-save-science/", "published_at": "2018-11-18T15:15:17+00:00" }, { "id": "01a0c518-bd69-7117-9da3-7ade7bac3468", "title": "Your Lab is Closer to the Bedside Than You Think", "url": "https://dirnagl.com/2018/10/19/your-lab-is-closer-to-the-bedside-than-you-think/", "published_at": "2018-10-19T05:06:47+00:00" }, { "id": "01a0c518-bd69-7117-9da3-7ade7c19990f", "title": "Predators in the (paper) forest", "url": "https://dirnagl.com/2018/09/17/predators-in-the-paper-forest/", "published_at": "2018-09-17T17:33:35+00:00" }, { "id": "01a0c518-bd69-7117-9da3-7ade7d06f441", "title": "No scientific progress without non-reproducibility?", "url": "https://dirnagl.com/2018/07/07/no-scientific-progress-without-non-reproducibility/", "published_at": "2018-07-07T13:29:43+00:00" }, { "id": "01a0c523-bd4f-72ba-ab63-471997272886", "title": "Train PIs and Professors!", "url": "https://dirnagl.com/2018/06/16/train-pis-and-professors/", "published_at": "2018-06-16T13:33:21+00:00" }, { "id": "01a0c523-bd50-7321-a4e6-598ee62023ed", "title": "Can (Non)-Replication be a Sin?", "url": "https://dirnagl.com/2018/05/16/can-non-replication-be-a-sin/", "published_at": "2018-05-16T09:20:36+00:00" }, { "id": "01a0c523-bd50-7321-a4e6-598ee6dbdedf", "title": "When you come to a fork in the road: Take it", "url": "https://dirnagl.com/2018/04/10/when-you-come-to-a-fork-in-the-road-take-it/", "published_at": "2018-04-10T10:53:14+00:00" }, { "id": "01a0c523-bd50-7321-a4e6-598ee7d66844", "title": "Of Mice, Macaques and Men", "url": "https://dirnagl.com/2018/03/18/of-mice-macaques-and-men/", "published_at": "2018-03-18T12:44:20+00:00" }, { "id": "01a0c523-bd50-7321-a4e6-598ee892fb49", "title": "Believe it or not!", "url": "https://dirnagl.com/2018/02/09/believe-it-or-not/", "published_at": "2018-02-09T16:38:07+00:00" }, { "id": "01a0c523-bd50-7321-a4e6-598ee9064af6", "title": "And the Moral of the Story is: Don’t believe your p-values!", "url": "https://dirnagl.com/2017/12/12/and-the-moral-of-the-story-is-dont-believe-your-p-values/", "published_at": "2017-12-12T17:58:39+00:00" }, { "id": "01a0c523-bd50-7321-a4e6-598ee9eaef65", "title": "Don’t ask what your Experiment can do for You: Ask what You can do for your Experiment!", "url": "https://dirnagl.com/2017/11/22/dont-ask-what-your-experiment-can-do-for-you-ask-what-you-can-do-for-your-experiment/", "published_at": "2017-11-22T12:43:13+00:00" }, { "id": "01a0c523-bd50-7321-a4e6-598eea5f48b4", "title": "“Next we….” – The history and perils of scientific storytelling", "url": "https://dirnagl.com/2017/10/28/next-we-the-history-and-perils-of-scientific-storytelling/", "published_at": "2017-10-28T17:35:15+00:00" }, { "id": "01a0c523-bd50-7321-a4e6-598eeb2476b5", "title": "Excellence vs. Soundness: If we want breakthrough science, we need to fund ‘normal science’", "url": "https://dirnagl.com/2017/09/23/excellence-vs-soundness-if-we-want-breakthrough-science-we-need-to-fund-normal-science/", "published_at": "2017-09-23T14:11:59+00:00" }, { "id": "01a0c523-bd50-7321-a4e6-598eeb39ead7", "title": "Start your own funding organization!", "url": "https://dirnagl.com/2017/07/01/start-your-own-funding-organization/", "published_at": "2017-07-01T14:08:38+00:00" }, { "id": "01a0c52f-4aab-71bd-9d8f-eaadb9fdddf3", "title": "For risks and side effects consult your librarian", "url": "https://dirnagl.com/2017/05/26/for-risks-and-side-effects-consult-your-librarian/", "published_at": "2017-05-26T12:28:36+00:00" }, { "id": "01a0c52f-4aab-71bd-9d8f-eaadbabdad9e", "title": "How original are your scientific hypotheses really?", "url": "https://dirnagl.com/2017/04/13/how-original-are-your-scientific-hypotheses-really/", "published_at": "2017-04-13T10:17:20+00:00" }, { "id": "01a0c52f-4aab-71bd-9d8f-eaadbb19ba94", "title": "And now for something completely different: Sequential designs in preclinical research", "url": "https://dirnagl.com/2017/03/12/and-now-for-something-completely-different-sequential-designs-in-preclinical-research/", "published_at": "2017-03-12T20:49:12+00:00" }, { "id": "01a0c52f-4aab-71bd-9d8f-eaadbbedc6b8", "title": "Lost access to Elsevier journals?", "url": "https://dirnagl.com/2017/01/21/lost-access-to-elsevier-journals/", "published_at": "2017-01-21T17:52:03+00:00" }, { "id": "01a0c52f-4aab-71bd-9d8f-eaadbce4eba2", "title": "Could a neuroscientist understand a computer?", "url": "https://dirnagl.com/2017/01/21/could-a-neuroscientist-understand-a-computer/", "published_at": "2017-01-21T16:58:55+00:00" }, { "id": "01a0c52f-4aab-71bd-9d8f-eaadbd8d537e", "title": "A Laboratory Critical Incident and Error Reporting System for Experimental Biomedicine", "url": "https://dirnagl.com/2016/12/05/a-laboratory-critical-incident-and-error-reporting-system-for-experimental-biomedicine/", "published_at": "2016-12-05T20:12:06+00:00" }, { "id": "01a0c52f-4aab-71bd-9d8f-eaadbe57321c", "title": "Ich glaub mich trifft der Schlag….", "url": "https://dirnagl.com/2016/11/08/ich-glaub-mich-trifft-der-schlag/", "published_at": "2016-11-08T20:44:21+00:00" }, { "id": "01a0c52f-4aab-71bd-9d8f-eaadbedcc69b", "title": "Hot off the press: 2nd Edition ‘Rodent Models of Stroke’", "url": "https://dirnagl.com/2016/09/27/hot-off-the-press-2nd-edition-rodent-models-of-stroke/", "published_at": "2016-09-27T17:23:33+00:00" }, { "id": "01a0c52f-4aab-71bd-9d8f-eaadbf8b0f8b", "title": "Radio Feature zu ‘Gender-Imbalance’ bei Tierversuchen (in German)", "url": "https://dirnagl.com/2016/08/18/radio-feature-zu-gender-imbalance-bei-tierversuchen-in-german/", "published_at": "2016-08-18T10:12:01+00:00" }, { "id": "01a0c52f-4aab-71bd-9d8f-eaadbfa965ad", "title": "Is Translational Stroke Research Broken, and if So, How Can We Fix It?", "url": "https://dirnagl.com/2016/07/09/is-translational-stroke-research-broken-and-if-so-how-can-we-fix-it/", "published_at": "2016-07-09T09:54:57+00:00" }, { "id": "01a0c539-9a45-7098-882b-82375404261a", "title": "The Relative Citation Ratio: It won’t do your laundry, but can it exorcise the journal impact factor?", "url": "https://dirnagl.com/2016/06/23/the-relative-citation-ratio-it-wont-do-your-laundry-but-can-it-exorcise-the-journal-impact-factor/", "published_at": "2016-06-23T13:58:44+00:00" }, { "id": "01a0c539-9a45-7098-882b-823754196435", "title": "Podcast ‘Vertrauen und Kontrolle in der Wissenschaft’", "url": "https://dirnagl.com/2016/04/24/podcat-vertrauen-und-kontrolle-in-der-wissenschaft/", "published_at": "2016-04-24T15:06:33+00:00" }, { "id": "01a0c539-9a45-7098-882b-8237550d5af4", "title": "Gut microbiota impact on stroke outcome: Fad or fact?", "url": "https://dirnagl.com/2016/03/06/gut-microbiota-impact-on-stroke-outcome-fad-or-fact/", "published_at": "2016-03-06T16:30:23+00:00" }, { "id": "01a0c539-9a45-7098-882b-82375606ee6c", "title": "SCI-HUB: The beginning of the end of publishing as we know it?", "url": "https://dirnagl.com/2016/02/25/sci-hub-the-beginning-of-the-end-of-publishing-as-we-know-it/", "published_at": "2016-02-25T21:06:21+00:00" }, { "id": "01a0c539-9a45-7098-882b-823756e9dc70", "title": "A pocket guide to electronic laboratory notebooks", "url": "https://dirnagl.com/2016/01/29/a-pocket-guide-to-electronic-laboratory-notebooks/", "published_at": "2016-01-29T17:06:24+00:00" }, { "id": "01a0c539-9a45-7098-882b-823757e41205", "title": "Where have all the rodents gone?", "url": "https://dirnagl.com/2016/01/06/where-have-all-the-rodents-gone/", "published_at": "2016-01-06T16:19:59+00:00" }, { "id": "01a0c539-9a45-7098-882b-823758b93893", "title": "BIAS!", "url": "https://dirnagl.com/2015/10/14/bias/", "published_at": "2015-10-14T20:24:26+00:00" }, { "id": "01a0c539-9a45-7098-882b-8237594db86d", "title": "Wenn Forschung nicht hält, was sie verspricht", "url": "https://dirnagl.com/2015/09/20/wenn-forschung-nicht-halt-was-sie-verspricht/", "published_at": "2015-09-20T16:00:46+00:00" }, { "id": "01a0c539-9a45-7098-882b-823759f65ea7", "title": "Trust but verify: Institutions must do their part for reproducibility", "url": "https://dirnagl.com/2015/09/02/trust-but-verify-institutions-must-do-their-part-for-reproducibility/", "published_at": "2015-09-02T09:40:03+00:00" }, { "id": "01a0c539-9a45-7098-882b-82375a73b574", "title": "Replication crisis, continued", "url": "https://dirnagl.com/2015/08/31/replication-crisis-continued/", "published_at": "2015-08-31T15:12:42+00:00" }, { "id": "01a0c542-e6c7-7323-b7f3-0b482304fa83", "title": "The “Broken Science” (aka “waste”) debate: A personal cheat sheet", "url": "https://dirnagl.com/2015/04/07/the-broken-science-aka-waste-debate-a-personal-cheat-sheet/", "published_at": "2015-04-07T05:11:37+00:00" }, { "id": "01a0c542-e6c7-7323-b7f3-0b4823e0ef98", "title": "“Translational research may be most successful when it fails”: The efficiency of translation in biomedicine", "url": "https://dirnagl.com/2015/02/09/the-efficiency-of-translation-in-biomedicine-on-the-relationships-of-waste-attrition-and-evidence/", "published_at": "2015-02-09T20:55:12+00:00" }, { "id": "01a0c542-e6c7-7323-b7f3-0b48243fa53d", "title": "Are scientific papers actually read?", "url": "https://dirnagl.com/2015/01/25/are-scientific-papers-actually-read/", "published_at": "2015-01-25T18:34:44+00:00" }, { "id": "01a0c542-e6c7-7323-b7f3-0b482530575e", "title": "The art of motorcycle maintenance", "url": "https://dirnagl.com/2014/12/15/the-art-of-motorcycle-maintenance/", "published_at": "2014-12-15T14:23:35+00:00" }, { "id": "01a0c542-e6c7-7323-b7f3-0b48256255d6", "title": "Replication and post-publication review: Four best practice examples", "url": "https://dirnagl.com/2014/12/14/replication-and-post-publication-review-four-best-practice-examples/", "published_at": "2014-12-14T11:34:13+00:00" }, { "id": "01a0c542-e6c7-7323-b7f3-0b482632a92f", "title": "Should we trust scientists? The case for peer auditing", "url": "https://dirnagl.com/2014/12/09/should-we-trust-scientists-the-case-for-peer-auditing/", "published_at": "2014-12-09T20:31:45+00:00" }, { "id": "01a0c542-e6c7-7323-b7f3-0b4826e354d9", "title": "Journals unite for reproducibility", "url": "https://dirnagl.com/2014/11/09/journals-unite-for-reproducibility/", "published_at": "2014-11-09T12:54:25+00:00" }, { "id": "01a0c542-e6c7-7323-b7f3-0b4827d7cdce", "title": "PubMed Commons to the rescue", "url": "https://dirnagl.com/2014/11/04/pubmed-commons-to-the-rescue/", "published_at": "2014-11-04T17:28:19+00:00" }, { "id": "01a0c542-e6c7-7323-b7f3-0b48280056d9", "title": "Appraising and rewarding biomedical research", "url": "https://dirnagl.com/2014/11/03/appraising-and-rewarding-biomedical-research/", "published_at": "2014-11-03T13:08:22+00:00" }, { "id": "01a0c542-e6c7-7323-b7f3-0b482818f2a8", "title": "10 years after: Ioannidis revisits his classic paper", "url": "https://dirnagl.com/2014/10/23/10-years-after-ioannidis-revisits-his-classic-paper/", "published_at": "2014-10-23T11:12:17+00:00" }, { "id": "01a0c54b-d4ff-710b-a7bc-0255883c16cc", "title": "p-value vs. positive predictive value", "url": "https://dirnagl.com/2014/09/22/p-value-vs-positive-predictive-value/", "published_at": "2014-09-22T20:50:10+00:00" }, { "id": "01a0c54b-d4ff-710b-a7bc-025588426afb", "title": "Pick one: Genomic responses in mouse models POORLY/GREATLY mimic human inflammatory diseases", "url": "https://dirnagl.com/2014/09/11/pick-one-genomic-responses-in-mouse-models-poorlygreatly-mimic-human-inflammatory-diseases/", "published_at": "2014-09-11T20:49:31+00:00" }, { "id": "01a0c54b-d4ff-710b-a7bc-02558860735f", "title": "Sind die meisten Forschungsergebnisse tatsächlich falsch?", "url": "https://dirnagl.com/2014/07/29/sind-die-meisten-forschungsergebnisse-tatsachlich-falsch/", "published_at": "2014-07-29T15:29:53+00:00" }, { "id": "01a0c54b-d4ff-710b-a7bc-025588cc9073", "title": "Higgs’ boson and the certainty of knowledge", "url": "https://dirnagl.com/2014/07/28/higgs-boson-and-the-certainty-of-knowledge/", "published_at": "2014-07-28T15:28:17+00:00" }, { "id": "01a0c54b-d4ff-710b-a7bc-02558950132f", "title": "Can mice be trusted?", "url": "https://dirnagl.com/2014/07/25/can-mice-be-trusted/", "published_at": "2014-07-25T11:06:12+00:00" }, { "id": "01a0c54b-d4ff-710b-a7bc-02558a134eff", "title": "Quality assurance and management in experimental research", "url": "https://dirnagl.com/2014/07/22/quality-assurance-and-management-in-experimental-research/", "published_at": "2014-07-22T11:32:40+00:00" }, { "id": "01a0c54b-d4ff-710b-a7bc-02558a6ddac4", "title": "Why post-hoc power calculation is not helpful", "url": "https://dirnagl.com/2014/07/14/why-post-hoc-power-calculation-does-not-help/", "published_at": "2014-07-14T08:54:16+00:00" }, { "id": "01a0c54b-d4ff-710b-a7bc-02558ad85d7a", "title": "Post-publication commenting", "url": "https://dirnagl.com/2014/07/07/post-publication-commenting/", "published_at": "2014-07-07T15:48:35+00:00" }, { "id": "01a0c54b-d4ff-710b-a7bc-02558bc8b0e2", "title": "Loose cable, significant at p", "url": "https://dirnagl.com/2014/06/30/loose-cable-significant-at-p0-0000002/", "published_at": "2014-06-30T15:38:56+00:00" }, { "id": "01a0c54b-d4ff-710b-a7bc-02558cbc4e2e", "title": "Sloppyness and effect size correlate linearly in clinical stem cell trials", "url": "https://dirnagl.com/2014/06/15/sloppyness-and-effect-size-correlate-linearly-in-clinical-stem-cell-trials/", "published_at": "2014-06-15T16:37:11+00:00" }, { "id": "01a0c554-2242-71bb-b260-1fe99c030649", "title": "Exploratory and confirmatory preclinical research", "url": "https://dirnagl.com/2014/05/30/exploratory-and-confirmatory-preclinical-research/", "published_at": "2014-05-30T13:07:35+00:00" }, { "id": "01a0c554-2242-71bb-b260-1fe99c35a5f8", "title": "Blogging as a form of postpublication review", "url": "https://dirnagl.com/2014/05/29/blogging-as-a-form-of-postpublication-review/", "published_at": "2014-05-29T15:23:15+00:00" }, { "id": "01a0c554-2242-71bb-b260-1fe99cfeda3d", "title": "Systemic flaws of biomedical research ecosystem", "url": "https://dirnagl.com/2014/05/18/434/", "published_at": "2014-05-18T09:02:46+00:00" }, { "id": "01a0c554-2242-71bb-b260-1fe99da1fe8d", "title": "Correlation vs causation", "url": "https://dirnagl.com/2014/05/18/432/", "published_at": "2014-05-18T08:48:20+00:00" }, { "id": "01a0c554-2242-71bb-b260-1fe99e8c3fff", "title": "Due dilligence in ALS research", "url": "https://dirnagl.com/2014/04/17/due-dilligence-in-als-research/", "published_at": "2014-04-17T08:33:20+00:00" }, { "id": "01a0c554-2242-71bb-b260-1fe99ebe494d", "title": "Have the ARRIVE guidelines been implemented?", "url": "https://dirnagl.com/2014/04/17/have-the-arrive-guidelines-been-implemented/", "published_at": "2014-04-17T08:01:34+00:00" }, { "id": "01a0c554-2242-71bb-b260-1fe99f389e39", "title": "Found in translation", "url": "https://dirnagl.com/2014/03/23/found-in-translation/", "published_at": "2014-03-23T22:15:44+00:00" }, { "id": "01a0c554-2242-71bb-b260-1fe99f9c219c", "title": "Nachkochen unmöglich", "url": "https://dirnagl.com/2014/03/23/nachkochen-unmoglich/", "published_at": "2014-03-23T22:00:56+00:00" }, { "id": "01a0c554-2242-71bb-b260-1fe99fe1f703", "title": "METRICS", "url": "https://dirnagl.com/2014/03/23/395/", "published_at": "2014-03-23T21:46:08+00:00" }, { "id": "01a0c554-2242-71bb-b260-1fe9a08ab29c", "title": "The probability of replicating ‘true’ findings is low…", "url": "https://dirnagl.com/2014/02/23/the-probability-of-replicating-true-findings-is-low/", "published_at": "2014-02-23T17:31:37+00:00" }, { "id": "01a0c55c-800e-7246-bbd0-6c81c8a18d9a", "title": "Open evaluation of scientific papers", "url": "https://dirnagl.com/2014/01/28/open-evaluation-of-scientific-papers/", "published_at": "2014-01-28T10:49:11+00:00" }, { "id": "01a0c55c-800e-7246-bbd0-6c81c8f00978", "title": "Otto Warburg’s research grant", "url": "https://dirnagl.com/2014/01/14/otto-warburgs-research-grant/", "published_at": "2014-01-14T12:31:06+00:00" }, { "id": "01a0c55c-800e-7246-bbd0-6c81c9058e33", "title": "Is more than 80% of medical research waste?", "url": "https://dirnagl.com/2014/01/09/is-more-than-80-of-medical-research-waste/", "published_at": "2014-01-09T12:07:20+00:00" }, { "id": "01a0c55c-800e-7246-bbd0-6c81c9ac4735", "title": "How Science goes wrong", "url": "https://dirnagl.com/2013/10/22/how-science-goes-wrong/", "published_at": "2013-10-22T21:19:27+00:00" }, { "id": "01a0c55c-800e-7246-bbd0-6c81ca790d19", "title": "The failure of peer review – A game of chance?", "url": "https://dirnagl.com/2013/10/10/the-failure-of-peer-review-a-game-of-chance/", "published_at": "2013-10-10T12:12:39+00:00" }, { "id": "01a0c55c-800e-7246-bbd0-6c81cb560796", "title": "Too good to be true: Excess significance in experimental neuroscience", "url": "https://dirnagl.com/2013/09/22/too-good-to-be-true-excess-significance-in-experimental-neuroscience/", "published_at": "2013-09-22T17:48:01+00:00" }, { "id": "01a0c55c-800e-7246-bbd0-6c81cbe3792b", "title": "How physics and engineering resolve reproducibility issues", "url": "https://dirnagl.com/2013/07/23/336/", "published_at": "2013-07-23T11:32:36+00:00" }, { "id": "01a0c55c-800e-7246-bbd0-6c81cc8dbd64", "title": "Call for international collaboration in preclinical research", "url": "https://dirnagl.com/2013/06/19/call-for-international-collaboration-in-preclinical-research/", "published_at": "2013-06-19T12:49:40+00:00" }, { "id": "01a0c55c-800e-7246-bbd0-6c81cd3349be", "title": "Overcoming negative (positive) publication bias", "url": "https://dirnagl.com/2013/06/12/155/", "published_at": "2013-06-12T08:31:37+00:00" }, { "id": "01a0c55c-800e-7246-bbd0-6c81cdc74814", "title": "Impact factor mania", "url": "https://dirnagl.com/2013/05/17/impact-factor-mania/", "published_at": "2013-05-17T14:43:13+00:00" } ] posts Claim your blog
Back to dirnagl.com
Blog · corpus.blog/blogs/dirnagl.com/posts

dirnagl.com

dirnagl.com

2025

Much Ado About Personalized Medicine… or Why the Nose of Biomedical Research Keeps Growing Longeroriginal ↗
18 Jun 2025
„Research Trek – Aufbruch in ein unbekanntes Wissenschaftssystem“original ↗
17 Jun 2025
AI in Medicine: Hubris, Hype, and Half-Scienceoriginal ↗
12 Apr 2025

2023

Artificial intelligence: Critique of chatty reasoningoriginal ↗
6 Jun 2023
Fraud in science is rare. But is this actually true?original ↗
12 Mar 2023

2021

Boost your score: Digital narcissism in the competition of scientistsoriginal ↗
3 May 2021
In the fight against Corona, learning from Botswana means learning to win!original ↗
18 Mar 2021
Judging science by proxies Part II: Back to the futureoriginal ↗
13 Mar 2021
Jugdging science by proxies: A short and incomplete historyoriginal ↗
3 Jan 2021

2020

Peer review is dead, long live peer review!original ↗
28 Nov 2020
Science meets politics, or: Survival of the ideas that fitoriginal ↗
14 Nov 2020
From mouse to man through the valley of death?original ↗
2 Sept 2020
Podcast maniaoriginal ↗
10 Aug 2020
“The Ioannidis Affair”original ↗
1 Jun 2020
We don’t need animal experiments! We get our drugs from the pharmacy!original ↗
1 Apr 2020
World sensation: Increase in life expectancy by more than 10 years!original ↗
13 Feb 2020

2019

Diet: Is nutrition science a more reliable source of advice than your grandmother?original ↗
15 Dec 2019
Why do WE trust the Intergovernmental Panel on Climate Change, but not the climate skeptics?original ↗
17 Nov 2019
What you always wanted to know about the p-value, but were afraid to askoriginal ↗
22 Oct 2019
When carmakers hack brainsoriginal ↗
13 Sept 2019
Love thy NULL result as thy statistically most significant!original ↗
12 May 2019
Nature: Pig brains kept alive outside body for hours after death! Really?original ↗
17 Apr 2019
Enter the funding lottery!original ↗
13 Apr 2019
On triangulation in experimentationoriginal ↗
16 Mar 2019
Man errs as long as he strives….original ↗
17 Feb 2019

2018

Microbe Mania with Melancholic Microbesoriginal ↗
16 Dec 2018
Could gambling save science?original ↗
18 Nov 2018
Your Lab is Closer to the Bedside Than You Thinkoriginal ↗
19 Oct 2018
Predators in the (paper) forestoriginal ↗
17 Sept 2018
No scientific progress without non-reproducibility?original ↗
7 Jul 2018
Train PIs and Professors!original ↗
16 Jun 2018
Can (Non)-Replication be a Sin?original ↗
16 May 2018
When you come to a fork in the road: Take itoriginal ↗
10 Apr 2018
Of Mice, Macaques and Menoriginal ↗
18 Mar 2018
Believe it or not!original ↗
9 Feb 2018

2017

And the Moral of the Story is: Don’t believe your p-values!original ↗
12 Dec 2017
Don’t ask what your Experiment can do for You: Ask what You can do for your Experiment!original ↗
22 Nov 2017
“Next we….” – The history and perils of scientific storytellingoriginal ↗
28 Oct 2017
Excellence vs. Soundness: If we want breakthrough science, we need to fund ‘normal science’original ↗
23 Sept 2017
Start your own funding organization!original ↗
1 Jul 2017
For risks and side effects consult your librarianoriginal ↗
26 May 2017
How original are your scientific hypotheses really?original ↗
13 Apr 2017
And now for something completely different: Sequential designs in preclinical researchoriginal ↗
12 Mar 2017
Lost access to Elsevier journals?original ↗
21 Jan 2017
Could a neuroscientist understand a computer?original ↗
21 Jan 2017

2016

A Laboratory Critical Incident and Error Reporting System for Experimental Biomedicineoriginal ↗
5 Dec 2016
Ich glaub mich trifft der Schlag….original ↗
8 Nov 2016
Hot off the press: 2nd Edition ‘Rodent Models of Stroke’original ↗
27 Sept 2016
Radio Feature zu ‘Gender-Imbalance’ bei Tierversuchen (in German)original ↗
18 Aug 2016
Is Translational Stroke Research Broken, and if So, How Can We Fix It?original ↗
9 Jul 2016
The Relative Citation Ratio: It won’t do your laundry, but can it exorcise the journal impact factor?original ↗
23 Jun 2016
Podcast ‘Vertrauen und Kontrolle in der Wissenschaft’original ↗
24 Apr 2016
Gut microbiota impact on stroke outcome: Fad or fact?original ↗
6 Mar 2016
SCI-HUB: The beginning of the end of publishing as we know it?original ↗
25 Feb 2016
A pocket guide to electronic laboratory notebooksoriginal ↗
29 Jan 2016
Where have all the rodents gone?original ↗
6 Jan 2016

2015

BIAS!original ↗
14 Oct 2015
Wenn Forschung nicht hält, was sie versprichtoriginal ↗
20 Sept 2015
Trust but verify: Institutions must do their part for reproducibilityoriginal ↗
2 Sept 2015
Replication crisis, continuedoriginal ↗
31 Aug 2015
The “Broken Science” (aka “waste”) debate: A personal cheat sheetoriginal ↗
7 Apr 2015
“Translational research may be most successful when it fails”: The efficiency of translation in biomedicineoriginal ↗
9 Feb 2015
Are scientific papers actually read?original ↗
25 Jan 2015

2014

The art of motorcycle maintenanceoriginal ↗
15 Dec 2014
Replication and post-publication review: Four best practice examplesoriginal ↗
14 Dec 2014
Should we trust scientists? The case for peer auditingoriginal ↗
9 Dec 2014
Journals unite for reproducibilityoriginal ↗
9 Nov 2014
PubMed Commons to the rescueoriginal ↗
4 Nov 2014
Appraising and rewarding biomedical researchoriginal ↗
3 Nov 2014
10 years after: Ioannidis revisits his classic paperoriginal ↗
23 Oct 2014
p-value vs. positive predictive valueoriginal ↗
22 Sept 2014
Pick one: Genomic responses in mouse models POORLY/GREATLY mimic human inflammatory diseasesoriginal ↗
11 Sept 2014
Sind die meisten Forschungsergebnisse tatsächlich falsch?original ↗
29 Jul 2014
Higgs’ boson and the certainty of knowledgeoriginal ↗
28 Jul 2014
Can mice be trusted?original ↗
25 Jul 2014
Quality assurance and management in experimental researchoriginal ↗
22 Jul 2014
Why post-hoc power calculation is not helpfuloriginal ↗
14 Jul 2014
Post-publication commentingoriginal ↗
7 Jul 2014
Loose cable, significant at poriginal ↗
30 Jun 2014
Sloppyness and effect size correlate linearly in clinical stem cell trialsoriginal ↗
15 Jun 2014
Exploratory and confirmatory preclinical researchoriginal ↗
30 May 2014
Blogging as a form of postpublication revieworiginal ↗
29 May 2014
Systemic flaws of biomedical research ecosystemoriginal ↗
18 May 2014
Correlation vs causationoriginal ↗
18 May 2014
Due dilligence in ALS researchoriginal ↗
17 Apr 2014
Have the ARRIVE guidelines been implemented?original ↗
17 Apr 2014
Found in translationoriginal ↗
23 Mar 2014
Nachkochen unmöglichoriginal ↗
23 Mar 2014
METRICSoriginal ↗
23 Mar 2014
The probability of replicating ‘true’ findings is low…original ↗
23 Feb 2014
Open evaluation of scientific papersoriginal ↗
28 Jan 2014
Otto Warburg’s research grantoriginal ↗
14 Jan 2014
Is more than 80% of medical research waste?original ↗
9 Jan 2014

2013

How Science goes wrongoriginal ↗
22 Oct 2013
The failure of peer review – A game of chance?original ↗
10 Oct 2013
Too good to be true: Excess significance in experimental neuroscienceoriginal ↗
22 Sept 2013
How physics and engineering resolve reproducibility issuesoriginal ↗
23 Jul 2013
Call for international collaboration in preclinical researchoriginal ↗
19 Jun 2013
Overcoming negative (positive) publication biasoriginal ↗
12 Jun 2013
Impact factor maniaoriginal ↗
17 May 2013
Next